5+ Bedroom Homes Real Estate For Sale in Matlacha, FL

Stunning waterfront estate set on 2.24 acres in the heart of matlacha—truly a boater’s paradise just minutes from some of florida’s finest boating, including boca grande and sanibel. This turnkey 4, 021 sq ft residence offers 5 bedrooms, 4.5 baths, and a third-floor den with breathtaking 360° views of pine island and the surrounding bay, with water views gracing nearly every room. The fully updated interior showcases a custom kitchen, granite countertops, state-of-the-art appliances, new impact windows and doors (2023), and a charming wood-burning fireplace. Poolside, a detached guest suite provides a spacious private retreat with a full bath—ideal for guests, in-laws, or extended stays. The exterior is equally as impressive, featuring an expansive screened lanai, with a large pool and spa, overlooking the bay. This home has had a number of upgrades, including a new aluminum metal roof, hardie board siding, professional lighting, a new irrigation system and a new fence in 2025. For the boaters, this house includes a new covered metal roof 10, 000 lb. Boat lift, making those trips to boca grande and sanibel a breeze. The house also features a spacious 4 car garage, and a large slab for a boat or rv. This house sits extremely high, and has never flooded during any hurricanes! Offered fully furnished and turnkey, this exceptional property makes living the florida waterfront dream as effortless as it is extraordinary.